The Brown Lemur (Lemur fulvus mayottensis and L.f. mongoz) or "Maki" is particularly commonly on Mayotte. These highly social, fruit-eating and largely noctural primates are more widespread on Madagascar, although the Comoro animals belong to two endemic sub-species.

Unfortunately, a number of introduced mammals also occur on the archipelago. Among the more endearing is the Tenrec (Tenrec ecaudatus) of Madagascar, a small and spiny insectivore endemic to the Malagasy region and which is widely used as a food source.